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Uracil-DNA Glycosylase (UDG)

- Thermo-labile version- 


  • Removing uracil-containing DNA 
  • Elimination of carryover contamination 
  • Engineered for heat susceptible 
  • Best for real-time PCR with dUTP


Cat.No. Product Size
UDG1000 HelixZyme™ Uracil-DNA Glycosylase (UDG) 1,000 units
UDG5000 HelixZyme™ Uracil-DNA Glycosylase (UDG) 5,000 units

NanoHelix Uracil-DNA-glycosylase(UDG), also known as UNG, is an engineered E. coli enzyme catalyzing the hydrolysis of N-glcosylic bond between the uracil and sugar, leaving an apyrimidinic site in uracil-containing single or double-stranded DNA. This enzyme has been engineered to be more susceptible to high-temperature and inactivated easily during the dUTP containing PCR or real-time PCR. The wild-type of E. coli UDG is resistant to thermal inactivation. For PCR diagnosis, UDG can be used for efficient removal of carryover contaminated uracil-containing DNA. 

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