2014 Launching a new product #1
IgG Affinity Resin, IGBP(immunoglobulin binding peptide) immobilized sepharose resin, is designed for rapid one-step purification of immunoglobulin G(IgG) of human, rabbit and porcine. IGBP is a small synthetic peptide which has a high affinity specifically to the Fc region of IgG of human, rabbit, and porcine and thus substitutable for Protein A, a protein ligand used for the IgG purifications. Compared to chromatography on Protein A sorbents, elution from IgG affinity resin is achieved under relatively mild conditions (pH 3.5 ~ 4.0). Thus, aggregate formation is reduced and antibody activity is preserved. In addition, IGBP is a small synthetic peptide which has an advantage over biological ligand ; that is cheaper to produce, ligand leakage by enzymatic degradation is either eliminated or significantly reduced, and that can in general better withstand cleaning in place such as 0.1 M NaOH.